MAKATUSSIN SYROP CAN BE FUN FOR ANYONE

desvenlafaxine will increase the amount or impact of codeine by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Observe. Desvenlafaxine inhibits CYP2D6; with higher desvenlafaxine doses (ie, four hundred mg) lessen the CYP2D6 substrate dose by up to 50%; no dosage adjustment essential with desvenlafaxine doses seven consecutive times straig